Production Supervisor
Chemical Synthesis

About the Role

As Production Supervisor – Chemical Synthesis, you will oversee day-to-day manufacturing operations for API production at our Hosur Campus. You will lead shift teams through the execution of complex multi-step chemical synthesis batches, ensuring strict adherence to batch manufacturing records (BMRs), SOPs, and cGMP standards in an MHRA and EU GMP-certified facility.

This is a hands-on leadership role with direct accountability for product quality, team performance, EHS compliance, and production schedule adherence. You will work closely with R&D, QA, Engineering, and Stores teams to maintain seamless manufacturing operations.

Key Responsibilities

• Supervise synthesis operations across multiple glass-lined reactors and multipurpose production areas, ensuring all batches are executed in strict accordance with approved BMRs and SOPs
• Lead, motivate, and manage shift teams of 10–15 operators — provide on-the-floor guidance, resolve technical issues in real time, and conduct shift handover briefings
• Monitor and document in-process checks (pH, temperature, yield, purity) and escalate deviations from approved parameters promptly to QA and management
• Review and approve batch manufacturing records for completeness, accuracy, and GMP compliance prior to QA review
• Coordinate with QC for in-process sample submission and release, with Stores for material issuance and inventory accuracy, and with Engineering for equipment maintenance scheduling
• Investigate manufacturing deviations, conduct root cause analyses, and implement and track corrective and preventive actions (CAPAs)
• Ensure full compliance with EHS policies — manage chemical hazards, PPE usage, waste segregation, and emergency response procedures across all shift activities
• Support technology transfer activities — assist R&D in new process implementation at manufacturing scale, review transferred process parameters, and provide feedback from the shop floor
• Participate in MHRA, EU GMP, and WHO GMP regulatory inspections and internal audits as the production area representative

Qualifications & Experience

• B.Sc. or M.Sc. in Chemistry, Chemical Engineering, or a related discipline
• 4–7 years of experience in API production or chemical synthesis manufacturing in a pharmaceutical facility, with at least 2 years in a supervisory role
• Hands-on experience with glass-lined reactors, vacuum distillation units, centrifuges, and filtration equipment commonly used in API synthesis
• Strong understanding of cGMP requirements for API manufacturing per ICH Q7, MHRA, EU GMP Part II, and WHO GMP guidelines
• Proficiency in BMR review, deviation reporting, CAPA management, and change control procedures
• Experience with EHS management in a chemical manufacturing environment — knowledge of chemical hazard identification, HAZOP, and emergency response protocols
• Demonstrated leadership ability — experience managing shift teams, resolving conflicts, and driving accountability in a manufacturing setting
• Good documentation skills and ability to communicate clearly in written and verbal English